diff --git a/core/modules/content_translation/content_translation.admin.js b/core/modules/content_translation/content_translation.admin.js
index 463525b1bcfab54305e5d8bc2e966d89ff790b17..17b87001fc4658acda3eb623aa2a9437ee88f0c5 100644
--- a/core/modules/content_translation/content_translation.admin.js
+++ b/core/modules/content_translation/content_translation.admin.js
@@ -61,7 +61,10 @@
           $element = $fields.filter(filterFieldsList);
         }
 
-        if ($element[0].matches(`input[value="${column}"]:checked`)) {
+        if (
+          $element.length &&
+          $element[0].matches(`input[value="${column}"]:checked`)
+        ) {
           $fields.prop('checked', true).not($element).prop('disabled', true);
         } else {
           $fields.prop('disabled', false);
diff --git a/core/modules/content_translation/tests/src/FunctionalJavascript/ContentTranslationConfigUITest.php b/core/modules/content_translation/tests/src/FunctionalJavascript/ContentTranslationConfigUITest.php
new file mode 100644
index 0000000000000000000000000000000000000000..ed54b4527079e189541c7e85e7750b67222a9cb8
--- /dev/null
+++ b/core/modules/content_translation/tests/src/FunctionalJavascript/ContentTranslationConfigUITest.php
@@ -0,0 +1,47 @@
+<?php
+
+declare(strict_types=1);
+
+namespace Drupal\Tests\content_translation\FunctionalJavascript;
+
+use Drupal\FunctionalJavascriptTests\WebDriverTestBase;
+
+/**
+ * Tests that the content translation configuration javascript does't fail.
+ *
+ * @group content_translation
+ */
+class ContentTranslationConfigUITest extends WebDriverTestBase {
+
+  /**
+   * {@inheritdoc}
+   */
+  protected static $modules = ['content_translation', 'node'];
+
+  /**
+   * {@inheritdoc}
+   */
+  protected $defaultTheme = 'stark';
+
+  /**
+   * Use the minimal profile.
+   *
+   * @var string
+   */
+  protected $profile = 'standard';
+
+  /**
+   * Tests that the content translation configuration javascript does't fail.
+   */
+  public function testContentTranslationConfigUI() {
+    $content_translation_manager = $this->container->get('content_translation.manager');
+    $content_translation_manager->setEnabled('node', 'article', TRUE);
+    $this->rebuildContainer();
+
+    $admin = $this->drupalCreateUser([], NULL, TRUE);
+    $this->drupalLogin($admin);
+    $this->drupalGet('/admin/config/regional/content-language');
+    $this->failOnJavaScriptErrors();
+  }
+
+}