diff --git a/core/lib/Drupal/Core/CoreServiceProvider.php b/core/lib/Drupal/Core/CoreServiceProvider.php
index 8eb1ec913928bfbdd7f0cadc6ed21bfb7a4657c2..bd0db8db8103791d9677889a5bf740fb79b902ef 100644
--- a/core/lib/Drupal/Core/CoreServiceProvider.php
+++ b/core/lib/Drupal/Core/CoreServiceProvider.php
@@ -9,6 +9,7 @@
 use Drupal\Core\DependencyInjection\Compiler\CorsCompilerPass;
 use Drupal\Core\DependencyInjection\Compiler\DeprecatedServicePass;
 use Drupal\Core\DependencyInjection\Compiler\ContextProvidersPass;
+use Drupal\Core\DependencyInjection\Compiler\DevelopmentSettingsPass;
 use Drupal\Core\DependencyInjection\Compiler\ProxyServicesPass;
 use Drupal\Core\DependencyInjection\Compiler\StackedKernelPass;
 use Drupal\Core\DependencyInjection\Compiler\StackedSessionHandlerPass;
@@ -58,6 +59,8 @@ public function register(ContainerBuilder $container) {
     // list-building passes are operating on the post-alter services list.
     $container->addCompilerPass(new ModifyServiceDefinitionsPass());
 
+    $container->addCompilerPass(new DevelopmentSettingsPass());
+
     $container->addCompilerPass(new ProxyServicesPass());
 
     $container->addCompilerPass(new BackendCompilerPass());
@@ -93,6 +96,7 @@ public function register(ContainerBuilder $container) {
     $container->addCompilerPass(new PluginManagerPass());
 
     $container->addCompilerPass(new DeprecatedServicePass());
+
   }
 
   /**
diff --git a/core/lib/Drupal/Core/DependencyInjection/Compiler/DevelopmentSettingsPass.php b/core/lib/Drupal/Core/DependencyInjection/Compiler/DevelopmentSettingsPass.php
new file mode 100644
index 0000000000000000000000000000000000000000..15b8d73cd29c286edd2fa710ee9c862234d9b8f3
--- /dev/null
+++ b/core/lib/Drupal/Core/DependencyInjection/Compiler/DevelopmentSettingsPass.php
@@ -0,0 +1,44 @@
+<?php
+
+namespace Drupal\Core\DependencyInjection\Compiler;
+
+use Drupal\Core\Cache\NullBackendFactory;
+use Symfony\Component\DependencyInjection\Compiler\CompilerPassInterface;
+use Symfony\Component\DependencyInjection\ContainerBuilder;
+
+/**
+ * Defines a compiler pass to register development settings.
+ */
+class DevelopmentSettingsPass implements CompilerPassInterface {
+
+  /**
+   * {@inheritdoc}
+   */
+  public function process(ContainerBuilder $container) {
+    /** @var \Drupal\Core\State\StateInterface $state */
+    $state = $container->get('state');
+    $twig_debug = $state->get('twig_debug', FALSE);
+    $twig_cache_disable = $state->get('twig_cache_disable', FALSE);
+    if ($twig_debug || $twig_cache_disable) {
+      $twig_config = $container->getParameter('twig.config');
+      $twig_config['debug'] = $twig_debug;
+      $twig_config['cache'] = !$twig_cache_disable;
+      $container->setParameter('twig.config', $twig_config);
+    }
+
+    if ($state->get('disable_rendered_output_cache_bins', FALSE)) {
+      $cache_bins = ['page', 'dynamic_page_cache', 'render'];
+      if (!$container->hasDefinition('cache.backend.null')) {
+        $container->register('cache.backend.null', NullBackendFactory::class);
+      }
+      foreach ($cache_bins as $cache_bin) {
+        if ($container->has("cache.$cache_bin")) {
+          $container->getDefinition("cache.$cache_bin")
+            ->clearTag('cache.bin')
+            ->addTag('cache.bin', ['default_backend' => 'cache.backend.null']);
+        }
+      }
+    }
+  }
+
+}
diff --git a/core/modules/system/src/Form/DevelopmentSettingsForm.php b/core/modules/system/src/Form/DevelopmentSettingsForm.php
new file mode 100644
index 0000000000000000000000000000000000000000..282d0f02cf2face6b11721da415bc0b0a9f2f728
--- /dev/null
+++ b/core/modules/system/src/Form/DevelopmentSettingsForm.php
@@ -0,0 +1,152 @@
+<?php
+
+namespace Drupal\system\Form;
+
+use Drupal\Core\DrupalKernelInterface;
+use Drupal\Core\Form\FormBase;
+use Drupal\Core\Form\FormStateInterface;
+use Drupal\Core\State\StateInterface;
+use Symfony\Component\DependencyInjection\ContainerInterface;
+
+/**
+ * Configure development settings for this site.
+ *
+ * @internal
+ */
+class DevelopmentSettingsForm extends FormBase {
+
+  /**
+   * Constructs a new development settings form.
+   *
+   * @param \Drupal\Core\State\StateInterface $state
+   *   The state service.
+   * @param \Drupal\Core\DrupalKernelInterface $kernel
+   *   The Drupal kernel.
+   */
+  public function __construct(
+    protected StateInterface $state,
+    protected DrupalKernelInterface $kernel
+  ) {
+  }
+
+  /**
+   * {@inheritdoc}
+   */
+  public static function create(ContainerInterface $container) {
+    $instance = new static(
+      $container->get('state'),
+      $container->get('kernel')
+    );
+    $instance->setMessenger($container->get('messenger'));
+    return $instance;
+  }
+
+  /**
+   * {@inheritdoc}
+   */
+  public function getFormId() {
+    return 'development_settings_form';
+  }
+
+  /**
+   * {@inheritdoc}
+   */
+  public function buildForm(array $form, FormStateInterface $form_state) {
+    $form['description'] = [
+      '#plain_text' => $this->t('These settings should only be enabled on development environments and never on production.'),
+    ];
+
+    $twig_debug = $this->state->get('twig_debug', FALSE);
+    $twig_cache_disable = $this->state->get('twig_cache_disable', FALSE);
+    $twig_development_state_conditions = [
+      'input[data-drupal-selector="edit-twig-development-mode"]' => [
+        'checked' => TRUE,
+      ],
+    ];
+    $form['twig_development_mode'] = [
+      '#type' => 'checkbox',
+      '#title' => $this->t('Twig development mode'),
+      '#description' => $this->t('Exposes Twig development settings.'),
+      '#default_value' => $twig_debug || $twig_cache_disable,
+    ];
+    $form['twig_development'] = [
+      '#type' => 'fieldset',
+      '#title' => $this->t('Twig development mode'),
+      '#states' => [
+        'visible' => $twig_development_state_conditions,
+      ],
+    ];
+    $form['twig_development']['twig_debug'] = [
+      '#type' => 'checkbox',
+      '#title' => $this->t('Twig debug mode'),
+      '#description' => $this->t("Provides Twig's <code>dump()</code> function for debugging, outputs template suggestions to HTML comments, and automatically recompile Twig templates after changes."),
+      '#default_value' => $twig_debug,
+    ];
+    $form['twig_development']['twig_cache_disable'] = [
+      '#type' => 'checkbox',
+      '#title' => $this->t('Disable Twig cache'),
+      '#description' => $this->t('Twig templates are not cached and are always compiled when rendered.'),
+      '#default_value' => $twig_cache_disable,
+    ];
+    if (!$twig_debug && !$twig_cache_disable) {
+      $form['twig_development']['twig_debug']['#states'] = [
+        'checked' => $twig_development_state_conditions,
+      ];
+      $form['twig_development']['twig_cache_disable']['#states'] = [
+        'checked' => $twig_development_state_conditions,
+      ];
+    }
+
+    $form['disable_rendered_output_cache_bins'] = [
+      '#type' => 'checkbox',
+      '#title' => $this->t('Do not cache markup'),
+      '#description' => $this->t('Disables render cache, dynamic page cache, and page cache.'),
+      '#default_value' => $this->state->get('disable_rendered_output_cache_bins', FALSE),
+    ];
+
+    $form['actions']['#type'] = 'actions';
+    $form['actions']['submit'] = [
+      '#type' => 'submit',
+      '#value' => $this->t('Save settings'),
+      '#button_type' => 'primary',
+    ];
+
+    return $form;
+  }
+
+  /**
+   * {@inheritdoc}
+   */
+  public function submitForm(array &$form, FormStateInterface $form_state) {
+    $disable_rendered_output_cache_bins_previous = $this->state->get('disable_rendered_output_cache_bins', FALSE);
+    $disable_rendered_output_cache_bins = (bool) $form_state->getValue('disable_rendered_output_cache_bins');
+    if ($disable_rendered_output_cache_bins) {
+      $this->state->set('disable_rendered_output_cache_bins', TRUE);
+    }
+    else {
+      $this->state->delete('disable_rendered_output_cache_bins');
+    }
+
+    $twig_development_mode = (bool) $form_state->getValue('twig_development_mode');
+    $twig_development_previous = $this->state->getMultiple(['twig_debug', 'twig_cache_disable']);
+    $twig_development = [
+      'twig_debug' => (bool) $form_state->getValue('twig_debug'),
+      'twig_cache_disable' => (bool) $form_state->getValue('twig_cache_disable'),
+    ];
+    if ($twig_development_mode) {
+      $invalidate_container = $twig_development_previous !== $twig_development;
+      $this->state->setMultiple($twig_development);
+    }
+    else {
+      $invalidate_container = TRUE;
+      $this->state->deleteMultiple(array_keys($twig_development));
+    }
+
+    if ($invalidate_container || $disable_rendered_output_cache_bins_previous !== $disable_rendered_output_cache_bins) {
+      $this->kernel->invalidateContainer();
+    }
+
+    $this->messenger()->addStatus($this->t('The settings have been saved.'));
+  }
+
+}
diff --git a/core/modules/system/system.install b/core/modules/system/system.install
index c6513010faa03770c6ca3ab289e643e84f97a87a..635f152ea214eb927efe395c3796bb35f1c7cb17 100644
--- a/core/modules/system/system.install
+++ b/core/modules/system/system.install
@@ -1532,6 +1532,37 @@ function (callable $hook, string $module) use (&$module_list, $update_registry,
     }
   }
 
+  // Add warning when twig debug option is enabled.
+  if ($phase === 'runtime') {
+    $twig_debug = \Drupal::state()->get('twig_debug', FALSE);
+    $twig_cache_disable = \Drupal::state()->get('twig_cache_disable', FALSE);
+    if ($twig_debug || $twig_cache_disable) {
+      $requirements['twig_debug_enabled'] = [
+        'title' => t('Twig development mode'),
+        'value' => t('Twig development mode settings are turned on. Go to @link to disable them.', [
+          '@link' => Link::createFromRoute(
+            'development settings page',
+            'system.development_settings',
+          )->toString(),
+        ]),
+        'severity' => REQUIREMENT_WARNING,
+      ];
+    }
+    $render_cache_disabled = \Drupal::state()->get('disable_rendered_output_cache_bins', FALSE);
+    if ($render_cache_disabled) {
+      $requirements['render_cache_disabled'] = [
+        'title' => t('Markup caching disabled'),
+        'value' => t('Render cache, dynamic page cache, and page cache are bypassed. Go to @link to enable them.', [
+          '@link' => Link::createFromRoute(
+            'development settings page',
+            'system.development_settings',
+          )->toString(),
+        ]),
+        'severity' => REQUIREMENT_WARNING,
+      ];
+    }
+  }
+
   return $requirements;
 }
 
diff --git a/core/modules/system/system.links.menu.yml b/core/modules/system/system.links.menu.yml
index ad012550dc85526f564566ae855388df7860edd7..04357e8d57f1de22ddaf7b024d8a64e38bf10db4 100644
--- a/core/modules/system/system.links.menu.yml
+++ b/core/modules/system/system.links.menu.yml
@@ -76,6 +76,12 @@ system.performance_settings:
   description: 'Configure caching and bandwidth optimization.'
   route_name: system.performance_settings
   weight: -20
+system.development_settings:
+  title: Development settings
+  parent: system.admin_config_development
+  description: 'Configure theme development settings'
+  route_name: system.development_settings
+  weight: -19
 system.logging_settings:
   title: 'Logging and errors'
   parent: system.admin_config_development
diff --git a/core/modules/system/system.routing.yml b/core/modules/system/system.routing.yml
index 9e01d58469e7f566a677b613c9d5f59a742906ee..728b5c4f857f341d226752dbf10da23fca4aef6a 100644
--- a/core/modules/system/system.routing.yml
+++ b/core/modules/system/system.routing.yml
@@ -182,6 +182,14 @@ system.performance_settings:
   requirements:
     _permission: 'administer site configuration'
 
+system.development_settings:
+  path: '/admin/config/development/settings'
+  defaults:
+    _form: '\Drupal\system\Form\DevelopmentSettingsForm'
+    _title: 'Development settings'
+  requirements:
+    _permission: 'administer site configuration'
+
 system.file_system_settings:
   path: '/admin/config/media/file-system'
   defaults:
diff --git a/core/modules/system/tests/src/FunctionalJavascript/Form/DevelopmentSettingsFormTest.php b/core/modules/system/tests/src/FunctionalJavascript/Form/DevelopmentSettingsFormTest.php
new file mode 100644
index 0000000000000000000000000000000000000000..acd2899059d52563227276abfa8a59ad2bac9607
--- /dev/null
+++ b/core/modules/system/tests/src/FunctionalJavascript/Form/DevelopmentSettingsFormTest.php
@@ -0,0 +1,135 @@
+<?php
+
+namespace Drupal\Tests\system\FunctionalJavascript\Form;
+
+use Drupal\Core\Cache\NullBackend;
+use Drupal\Core\Url;
+use Drupal\FunctionalJavascriptTests\WebDriverTestBase;
+use Symfony\Component\HttpFoundation\Request;
+
+/**
+ * Tests development settings form items for expected behavior.
+ *
+ * @group Form
+ */
+class DevelopmentSettingsFormTest extends WebDriverTestBase {
+
+  /**
+   * {@inheritdoc}
+   */
+  protected static $modules = ['system', 'dynamic_page_cache', 'page_cache'];
+
+  /**
+   * {@inheritdoc}
+   */
+  protected $defaultTheme = 'stark';
+
+  /**
+   * {@inheritdoc}
+   */
+  protected function setUp(): void {
+    parent::setUp();
+
+    $admin_user = $this->drupalCreateUser([
+      'administer site configuration',
+    ]);
+    $this->drupalLogin($admin_user);
+  }
+
+  /**
+   * Tests turning on Twig development mode.
+   *
+   * @dataProvider twigDevelopmentData
+   */
+  public function testTwigDevelopmentMode(bool $twig_development_mode, ?bool $twig_debug, ?bool $twig_cache_disable): void {
+    $twig_debug = $twig_debug ?? $twig_development_mode;
+    $twig_cache_disable = $twig_cache_disable ?? $twig_development_mode;
+
+    $twig_config = \Drupal::getContainer()->getParameter('twig.config');
+    self::assertFalse($twig_config['debug']);
+    self::assertNull($twig_config['auto_reload']);
+    self::assertTrue($twig_config['cache']);
+
+    $this->drupalGet(Url::fromRoute('system.development_settings'));
+    if ($twig_development_mode) {
+      $this->getSession()->getPage()->checkField('Twig development mode');
+      $this->assertSession()->checkboxChecked('Twig debug mode');
+      $this->assertSession()->checkboxChecked('Disable Twig cache');
+    }
+    if (!$twig_debug) {
+      $this->getSession()->getPage()->uncheckField('Twig debug mode');
+    }
+    if (!$twig_cache_disable) {
+      $this->getSession()->getPage()->uncheckField('Disable Twig cache');
+    }
+    $this->getSession()->getPage()->pressButton('Save settings');
+
+    $this->drupalGet(Url::fromRoute('system.status'));
+    if (!$twig_development_mode) {
+      $this->assertSession()->pageTextNotContains('Twig development mode');
+    }
+    else {
+      $this->assertSession()->pageTextContains('Twig development mode');
+      $this->assertSession()->linkExists('development settings page');
+    }
+
+    $refreshed_container = $this->initKernel(Request::create('/'));
+    $twig_config = $refreshed_container->getParameter('twig.config');
+    self::assertEquals($twig_debug, $twig_config['debug']);
+    self::assertNull($twig_config['auto_reload']);
+    self::assertEquals(!$twig_cache_disable, $twig_config['cache']);
+  }
+
+  /**
+   * Test data for Twig development mode.
+   *
+   * @return array[]
+   */
+  public static function twigDevelopmentData(): array {
+    return [
+      'Twig development mode checked only' => [
+        TRUE,
+        NULL,
+        NULL,
+      ],
+      'Twig debug mode only, keep Twig cache' => [
+        TRUE,
+        TRUE,
+        FALSE,
+      ],
+      'Twig debug mode off, disable Twig cache' => [
+        TRUE,
+        FALSE,
+        TRUE,
+      ],
+      'No changes' => [
+        FALSE,
+        NULL,
+        NULL,
+      ],
+    ];
+  }
+
+  /**
+   * Tests disabling cache bins which cache markup.
+   */
+  public function testDisabledRenderedOutputCacheBins(): void {
+    self::assertFalse(\Drupal::getContainer()->has('cache.backend.null'));
+
+    $this->drupalGet(Url::fromRoute('system.development_settings'));
+    $this->getSession()->getPage()->checkField('Do not cache markup');
+    $this->getSession()->getPage()->pressButton('Save settings');
+
+    $this->drupalGet(Url::fromRoute('system.status'));
+    $this->assertSession()->pageTextContains('Markup caching disabled');
+    $this->assertSession()->linkExists('development settings page');
+
+    $refreshed_container = $this->initKernel(Request::create('/'));
+    self::assertTrue($refreshed_container->has('cache.backend.null'));
+    $cache_bins = ['page', 'dynamic_page_cache', 'render'];
+    foreach ($cache_bins as $cache_bin) {
+      self::assertInstanceOf(NullBackend::class, $refreshed_container->get("cache.$cache_bin"));
+    }
+  }
+
+}